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Deterministic Kinetics in Chemistry and Systems Biology

The Dynamics of Complex Reaction Networks

Gábor Lente

PDF
ca. 53,49

Springer International Publishing img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Theoretische Chemie

Beschreibung

This book gives a concise overview of the mathematical foundations of kinetics used in chemistry and systems biology. The analytical and numerical methods used to solve complex rate equations with the widely used deterministic approach will be described, with primary focus on practical aspects important in designing experimental studies and the evaluation of data. The introduction of personal computers transformed scientific attitudes in the last two decades considerably as computational power ceased to be a limiting factor. Despite this improvement, certain time-honored approximations in solving rate equations such as the pre-equilibrium or the steady-state approach are still valid and necessary as they concern the information content of measured kinetic traces. The book shows the role of these approximations in modern kinetics and will also describe some common misconceptions in this field.

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Schlagwörter

Deterministic Approach, Solving Rate Equations, Activation Parameters, Steady-state Approximation, Competition Kinetics, Solving Kinetic Equations, Statistical Kinetics, Approximations for Rate Equations, Complex Rate Equations, Systems Biology, Kinetics in Systems Biology, Rate Determining Step