Leseprobe
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Drug Design and Discovery
Surya K. De
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Naturwissenschaften, Medizin, Informatik, Technik / Genetik, Gentechnik
Beschreibung
This book covers the important role small molecules can play in the modulation of stress-activated protein kinase (SAPK), also called the mitogen-activated protein kinase (MAPK) pathway, and the potential this may offer in enabling the development of future medicine therapies. It is clear that MAP kinase pathway therapies could continue to drive increasing interest in the field, both within academic laboratories and also in the biotechnology and pharmaceutical sectors. This book provides an overview of protein kinase inhibitors, the biological roles of MAP kinases, ATP-competitive and non-competitive inhibitors, covalent inhibitors, and more. This book is intended for professors in academia, researchers in pharmaceutical and biotechnology sectors working on protein kinases, and graduate students in pharmacy/chemistry.
Kundenbewertungen
MAP Kinase signaling network, Bi-dentate inhibitors, Covalent inhibitors, Role of MAPK in rheumatoid arthritis, Stress-Activated protein kinase, Role of MAPK in bronchial asthma, Biological Roles of MAP kinases, Clinically Approved Drugs for Protein Kinases, Role of MAPK in Parkinson's Disease, Drug Design, Protein Kinase Inhibitors, Role of MAPK in oncology, ATP-competitive inhibitors, Drug Delivery, Role of MAPK in obesity and type-2 diabetes, Non-ATP site binding inhibitors, Mitogen-Activated Protein Kinase Inhibitors